Medicinal Chemistry Services / Organic Chemistry Services
Pharmacology Services
Averin biotech provides consulting services and strategic guidance in the drug design and discovery projects. Our staff are well qualified and deal with the below services.
- Creating compound candidate profiles
- Synthesizing new analogs
- Developing optimization strategies
- Improving compound properties
- Assessing drug-like properties of lead molecules
- Assessing the drug discovery progress
- IR analysis
- MASS Analysis
- FTIR Analysis
- LCMS Analysis
- NMR Analysis
- HPLC Analysis
- GC Analysis
- UV Analysis
- TLC Analysis (Thin Layer Chromatography Analysis)
- Column Chromatography & Purification Service
- HPTLC Analysis (High Performance Thin Layer Chromatography Analysis)
- Protein structure prediction
- Molecular dynamics simulation studies
- Molecular docking studies
- Qsar studies
- Fragment based drug designing services
- Pharmacophore mapping studies
- ADME and Toxicity studies
Pharmacology Services
In vivo Activity
DLA/EAC induced ascitic tumor model in mice
DLA induced solid tumor model in mice
In Vitro Activity
Cytotoxicity assay by MTT/SRB/Trypan blue
Clonogenic assay
Apoptosis – Nuclear staining with DAPI
Alkylating activity assay
TUNEL assay
Endonuclease assay
DNA fragmentation analysis / DNA ladder assay
Cancer specific gene expression analysis
P53, BCl2, Capsase 3, VEGF, cyclin D1, cyclin B1, STAT3 etc.
Anti Diabetes Activity ( In vivo Activity )
Alloxan induced diabetic rat model
Streptozotocin induced diabetic rat model
Glucose uptake studies in skeletal muscle cell lines (Non-radio labeled assay).
Glucose uptake in isolated rat hemi diaphragm
Gene expression studies (PPARγ, GLUT-4 etc)
Alpha-Amylase inhibitory activity
Alpha-galactosidase inhibitory activity
Alpha-glucosidase activity
Hepatoprotective Activity / In vivo Activity
Hepatoprotective study against selected toxicant in rats In Vitro Activity
Hepatoprotective study against selected toxicant.
Hepatoprotective study in isolated primary rat hepatocytes.
Gene expression studies
Anti infective Activity In vivo Activity
Different wound healing models in mice/rats
Anti microbial activity by Zone of inhibition.
Anti microbial activity by MIC determination
Antibiotic sensitivity testing
TLC bioautography
In vitro anti viral studies
Other in vivo services
Hypercholesterolemia
Arthritis
Osteoporosis
Benign prostatic Hyperplasia
Spermatogenesis
Allergy
Antitussive
Psoriasis
Other Services
Antimicrobial
Anti viral
Cytotoxicity
Cell proliferation
Cancer
Diabetes
Hepatoprotection
Obesity
Immunomodulatory
Inflammation
Skin whitening
Skin irritation (Dermal toxicity)
Psoriasis
Wound healing
Genotoxicity
Drug permeability
Gene expression analysis
Enzyme and Immunoassays (ELISA)
+91 92477.16307
